Glutamate accumulation in the photoreceptor-presumed final common path of photoreceptor cell death
Identifieur interne : 000D05 ( Main/Exploration ); précédent : 000D04; suivant : 000D06Glutamate accumulation in the photoreceptor-presumed final common path of photoreceptor cell death
Auteurs : Makoto Tamai [Japon]Source :
- Behavioral and Brain Sciences [ 0140-525X ] ; 1995-09.
Abstract
Genetic abnormalities of three factors related to the photoreceptor mechanism have been reported in both animal models and humans. Apoptotic mechanism has also been suggested as a final common pathway of photoreceptor cell death. Our findings of increased level of glutamate in photoreceptor cells in rds mice suggest that amino acid might mediate between these two pathological mechanisms.
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DOI: 10.1017/S0140525X00039480
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